Adaptation and validation of the Spanish version of the thyroid-cancer-specific Thyca-QoL scale: A cross-sectional study



Palabras clave:

neoplasias tiroideas, calidad de vida, comparación transcultural, estudio de validación, psicometría


Introduction. Thyca-QoL is a specific instrument to assess QoL in thyroid cancer patients, but it is not validated in Spanish language. The aim was to assess the psychometric properties of the Thyca-QoL.

Methods. This is a prospective cross-sectional study. The Thyca-QoL was translated and adapted to Spanish language. A psychometric validation using an exploratory principal axis factor analysis and confirmatory analysis, concurrent validation compared with EORTC QLQ-C30 and a test-retest reliability assessment was done.

Results. A total of 296 patients were included. Exploratory factor analysis showed a seven-factor solution with good diagnostic tests results. Cronbach´s alpha for the global scale was 0.86. The comparison between the ThycaQoL and the EORTC QLQ-C30 demonstrated a high correlation (rho= 0.75) and coefficient for test-retest was 0.87.

Discussion. The validation process followed all the methodological steps necessary to guarantee the performance of the instrument. The measurements of the internal validity, reliability and reproducibility reached similar results as the original validation. The factor analysis showed a solution with seven factors that resembles the original results. Reproducibility was high for voice, sympathetic, sex, and chilliness domains and moderate for the others and the instrument had the ability to discriminate between clinical conditions.

Conclusion. Thyca-QoL is a reliable and objective instrument to be used in clinical practice and for research objectives in Spanish speaking patients.


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Biografía del autor/a

Álvaro Sanabria, Departamento de Cirugia. Facultad de Medicina. Universidad de Antioquia

MD, PhD, General surgeon, Department of Surgery, School of Medicine, Universidad de Antioquia; Head and Neck Service, Fundación Colombiana de Cancerología-Clínica Vida.

Óscar Gómez, Universidad de Antioquia, Medellín, Colombia.

MD, General surgeon, Department of Surgery, School of Medicine.

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Cómo citar

Sanabria, Álvaro; Gómez, Óscar. Adaptation and Validation of the Spanish Version of the Thyroid-Cancer-Specific Thyca-QoL Scale: A Cross-Sectional Study. Rev Colomb Cir 2023, 38, 613-623.



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